Jeremy Kodanko

Jeremy Kodanko

Associate Chair
Associate Professor

313-577-9043

313-577-8822 (fax)

jkodanko@chem.wayne.edu

Chem 261

Websites

chem.wayne.edu/kodankogroup

Jeremy Kodanko

Research Interest/Area of Expertise

  • Organic synthesis, inorganic synthesis, metal-based drug design, catalysis, iron chemistry, ligand design and coordination chemistry.

Research

 

Research in the Kodanko laboratory is at the interface of organic, inorganic and medicinal chemistry. We are interested in harnessing the power of metal complexes for biological applications. Projects currently being conducted in the Kodanko laboratory span across many subdisciplines of chemistry research including organic and inorganic synthesis, catalysis, kinetic and mechanistic studies, coordination chemistry, enzyme inhibition and cell biology. Recent interests have focused on the development of light-activated compounds for biological research applications, and as potential therapeutics.

 

 

Education – Degrees, Licenses, Certifications

  • B.S., University of Wisconsin-Madison, 1998
  • Ph.D., University of California-Irvine, 2003
  • NIH Postdoctoral Fellow, Massachusetts Institute of Technology, 2003-6

Selected Publications

Li, A.; White, J. K.; Arora, K.; Herroon, M. K.; Martin, P. D.; Schlegel, H. B.; Podgorski, I.; Turro, C.; Kodanko, J. J. "Selective Release of Aromatic Heterocycles from Ruthenium Tris(2-pyridylmethyl)amine with Visible Light" Inorg. Chem. 2016, 55, 10.

Ramalho, S. D.; Sharma, R.; White, J. K.; Aggarwal, N.; Chalasani, A.; Sameni, M.; Moin, K.; Vieira, P. C.; Turro, C.; Kodanko, J. J.; Sloane, B. F. "Imaging sites of inhibition of proteolysis in pathomimetic human breast cancer cultures by light-activated ruthenium compound" PLoS One 201510, e0142527/1.

Sharma, R.; Knoll, J. D.; Ancona, N.; Martin, P. D.; Turro, C.; Kodanko, J. J. "Solid-Phase Synthesis as a Platform for the Discovery of New Ruthenium Complexes for Efficient Release of Photocaged Ligands with Visible Light" Inorg. Chem. 201554, 1901.

Respondek, T.; Sharma, R.; Herroon, M. K.; Garner, R. N.; Knoll, J. D.; Cueny, E.; Turro, C.; Podgorski, I.; Kodanko, J. J. "Inhibition of Cathepsin Activity in a Cell-Based Assay by a Light-Activated Ruthenium Compound" ChemMedChem 20149, 1306.

Respondek, T.; Garner, R. N.; Herroon, M. K.; Podgorski, I.; Turro, C.; Kodanko, J. J. "Light Activation of a Cysteine Protease Inhibitor: Caging of a Peptidomimetic Nitrile with RuII(bpy)2" J. Am. Chem. Soc. 2011133, 17164.

 

Courses taught

CHM 6240/7240   Organic Spectroscopy, 3 credit hours   F2016
CHM 7740   Responsible Conduct of Research, 1 credit hours   F2016