David Njus

David Njus



313-577-6891 (fax)


2125 Biological Sciences

Curriculum Vitae



David Njus

Research Interest/Area of Expertise

  • Mitochondrial function and aging

  • Cellular mechanisms of Parkinson's Disease

  • Non-enzymatic redox reactions and oxidative stress

Education – Degrees, Licenses, Certifications

  • B.S., Physics, Massachusetts Institute of Technology, 1970;
  • Ph.D. Biophysics, Harvard University, 1975;
  • Postdoctoral, Biochemistry, Oxford University, 1975-78

Selected Publications

Tu, Y.J., Njus, D., and Schlegel, H. B. (2017) A theoretical study of ascorbic acid oxidation and HOO• / O2-• radical scavenging, Org. Biomol. Chem. 15, 4417 – 4431.

Mehta, N.J., Asmaro, K., Hermiz, D.J., Njus, M.M., Saleh, A.H., Beningo, K.A., and Njus, D. (2016) Hypochlorite converts cysteinyl-dopamine into a cytotoxic product: A possible factor in Parkinson’s Disease, Free Radical Biology & Medicine 101, 44-52.

Alhasan, R., and Njus, D. (2008) The epinephrine assay for superoxide: Why dopamine does not work, Analytical Biochemistry 381, 142-147.

Li, G., Zhang, H., Sader, F., Vadhavkar, N., and Njus, D. (2007) Oxidation of 4-methylcatechol: Implications for the oxidation of catecholamines, Biochemistry 46, 6978-6983.

Barber, M., and Njus, D. (2007) Clicker evolution: Seeking Intelligent Design, CBE Life Sciences Education 6, 1-8.

Kipp, B.H., Faraj, C., Li, G., and Njus, D. (2004) Imidazole facilitates electron transfer from organic reductants, Bioelectrochemistry 64, 7-13.

Njus, D., Wigle, M., Kelley, P.M., Kipp, B.H., and Schlegel, H.B. (2001) Mechanism of ascorbic acid oxidation by cytochrome b561, Biochemistry 40, 11905-11911.

Kipp, B.H., Kelley, P.M., and Njus, D. (2001) Evidence for an essential histidine residue in the ascorbate binding site of cytochrome b561, Biochemistry 40, 3931-3937.

Courses taught

 BIO 3200, Human Physiology