Pramod Khosla

Pramod Khosla

Professor,
AAUP: Faculty Grievance Coordinator

313-577-0448

313-577-8616 (fax)

aa0987@wayne.edu

 Room 3002 Science Hall

Pramod Khosla

Department

Nutrition and Food Science

Dr. Khosla has been working on diet and lipoprotein metabolism for almost thirty years. After obtaining his BSc and MSc from Newcastle University in the UK and PhD from the University of Western Ontario in Canada, he did post-doctoral research at Brandeis University in the USA. Dr Khosla is the author of some 100 plus articles including original research, book chapters, reviews and commentaries. He has been involved in dietary-fat related research/education for several years and given over a hundred invited guest lectures and seminars in >30 countries. He has supervised 36 graduate students (PhD, MS and MA) and taught over eighty classes (11 different courses). Over the last few years, Dr Khosla’s laboratory has carried out studies in dialysis patients to look at the effects of various supplements (omega 3 fatty acids,  tocotrienols) on markers of inflammation, oxidative stress and blood lipids. He was the lead investigator on a multi-centered clinical trial involving various dialysis units in Michigan (Henry Ford, Great Lakes Dialysis, Davita) as well as Universiti Kebangsaan Malaysia (UKM)  and Universiti Putra Malaysia (UPM), evaluating the effects of tocotrienol supplementation on lipid, inflammatory and oxidative stress markers. He is also involved in various collaborative studies looking at various aspects of diet on protein energy wasting (PEW) as well as renal nutrition education in dialysis patients. This work, in addition to UKM and UPM, involves collaborative centers in the Bangladesh and Saudi Arabia.

Research interest(s)/area of expertise

Current research interests relate to the role of diet on a) lipoprotein metabolism ( in general) and b) specifically in chronic kidney disease (CKD) patients including those with end stage renal disease (ESRD) on maintenabce hemodialysis. Also interested on the effects of PEW in CKD.

Education

BSc (Hons) Physiology, MSc and PhD Biochemistry

Selected publications

Rahman, T., Khor, B.H., Sahathevan, S., Kaur, D., Latifi, E., Afroz, M., Mitali, E. J., Tashkandi, N., Begum, N. A. S., Kashem, T. S., Arefin, S. Ur Z., Daud, Z. A. M., Karupaiah, T., Rashid, H. Ur and Khosla, P. (2022) Protein Energy Wasting in a cohort of Maintenance hemodialysis patients in Dhaka, Bangladesh, Nutrients, 14, 1469 https://www.mdpi.com/2072-6643/14/7/1469

Rahman, T., Ahmed, S., Kabir, Md., R., Akhtaruzzaman, M., Mitali, E. J., Rashid, H.-Ur Rashid, Daud, Z. A. M., Khor, B.H., Kaur, D., and Khosla, P. (2022) Provision of renal-specific nutrition knowledge for changing dietary practice in Bangladeshi hemodialysis patients. PEC Innovation, 1, https://doi.org/10.1016/j.pecinn.2022.100028

Teong, L. F., Khor, B. H., Kristo, R. P., Gafor, A. H. A., Leong, G. B., Bee, B. C., Yahya, R., Bavanandam, S., Ng, H. M., Sahathevan, S., Narayanan, S. S., Daud, Z. A. M., Khosla, P. and Karupaiah, T. (2022) A mobile app for triangulating strategies in phosphate education targeting patients with chronic kidney disease: Development, validation and patient acceptance. Healthcare 10, 535-553. https://doi.org/10.3390/healthcare10030535

Sulaheen, A., Khor, B-H., Balasubramaniam, G. V., Sahathevan, S., Chinna, K., Daud, Z. A. M., Khosla, P., Gafor, A.H.A. and Karupaiah, T. (2022) Benchmarking Diet Quality to Assess Nutritional Risk in Hemodialysis Patients: Applying Adequacy and Moderation Metrics of the hemodialysis-Healthy Eating Index. J Renal Nutr. (online) https://doi.org/10.1053/j.jrn.2022.02.002

Ahmed, S., Rahman, T., Ripon Md. S. H., Rashid, H.-Ur, Kashem, T., Ali, Md., S. M., Khor, B-H, Khosla, P., Karupaiah, T. and Daud, Z. M. A. (2021) A Food Frequency Questionnaire for Hemodialysis Patients in Bangladesh (BDHD-FFQ): Development and Validation. Nutrients 13, https://www.mdpi.com/2072-6643/13/12/4521

Ng, H-M., Khor, B-H, Sahathevan, S., Sulaheen, A., Chinna, K., Gafor, A.H.A., Goh, B-l, Ahmad, G., Morad, Z., Daud, Z. A. M., Khosla, P. and Karupaiah, T. (2021) Is malnutrition a determining factor of health-related quality of life in hemodialysis patients? A cross-sectional design examining relationships with a comprehensive assessment of nutritional status. Q of Life Res., 10, 1007-1026.

Khor, B-H, Tallman, D. A., Karupaiah, T., Khosla, P., Chan, M. and Kopple, J. D. (2021) Nutritional Adequacy of Animal-based and Plant-Based Asian Diets for Chronic Kidney Disease Patients: A Modelling Study. Nutrients 13, 3341-3360.

Adanan, N. I. H., Adnan Md., W. A. H., Khosla, P., Karupaiah, T. and Daud, Z. M. A. (2021) Exploring the experiences and perceptions of hemodialysis patients observing Ramadan fasting: A Qualitative Study. BMC Nephrol. 22, 48-59

Khor, B-H., Sahathevan, S., Sulaheen, A., Ali, M.S.M., Narayanan, S. S., Chinna, K., Gafor, A.H.A, Goh, B-L., Ghazali, A., Morad, Z., Daud, Z.A.M., Khosla, P., Sundram, K. and Karupaiah, T.(2021) Circulating fatty acid profile are associated with protein energy wasting in maintenance hemodialysis patients: A cross sectional study. Sci. Rep. Int.11, 1416-1427

Md., Ali. M.S., Yeak, Z-W., Khor, B.-H., Sahathevan, S., Sulaheen, A., Lim, J.-H., Adanan, N.I.H., Gafor, A.H., Zakaria, N. F., Khosla, P., Karupaiah, T., Daud, Z. A. M. (2020) HD-FFQ to detect nutrient deficiencies and toxicities for a multiethnic Asian dialysis population. Nutrients, 12, 1585-1601:

Sahathevan, S., Khor, B.H., Singh, B.K.S., Sabatino, A., Fiaccadori, E., Daud, Z.A.M., Ali, M.S., Narayanan, S. S., Tallman, D., Chinna, K., Goh, B.L., Gafor, A. H. A., Ghazali, A., Morad, Z., Khosla, P., Karupaiah T. (2020) Association of ultrasound-derived metrics of the quadriceps muscle with protein energy wasting in hemodialysis patients: A multicenter cross-sectional study. Nutrients, 12, 3597-3613

Lim, J.H., Chinna, K., Khosla, P., Karupaiah, T. and Daud, Z. A. M. (2020) Understanding how nutrition literacy links to dietary adherence in hemodialysis patients: A theoretical exploration using partial least squares structural adherence modeling population. Int. J. Env. Res. Health Prom. 17, 7479-7499

Khor, B.H., Sulaheen, A., Sahathevan, S., Chinna, K., Gafor, A. H. Bavanandan, S., Goh, B.L., Morad, Z., Daud, Z.A.M., Khosla, P., Yee-Moon, A.. W. and Karupaiah, T. (2020) Association of dietary patterns with serum phosphorus in maintenance hemodialysis patients, Sci. Rep. Int., 10, 12278

Tallman, D.A., Latifi, E., Kaur, D., Sulaheen, A., Ikizler, T.A., Chinna, K., Daud, Z.A.M., Karupaiah, T. and Khosla, P. (2020) Dietary Patterns and Heath Outcomes Among African-American Maintenance Hemodialysis Patients. Nutrients, 12, 797-808.

Farhana, L., Sarkar, S., Nangia-Makker, P., Yu, Y., Khosla, P., Levi, E., Azmi, A. and Majumdar, A. P. N. (2020) Natural agents inhibit aggressive colon cancer tumor by restituting dysbiosis, PLoSOne, 15 (3), e0229823.

Kaur, D., Tallman, D. A., and Khosla, P. (2020) The Health Effects of Saturated Fats – The Role of Whole foods and Dietary Patterns. Diabetes Metab. Syndr. 14: 151-153.
 

Currently teaching

  • NFS 4230 Macronutrients
  • NFS 6000 Nutritional Biochemistry (team taught)

Courses taught

  • Previous courses taught in the department
  • NFS 2030 Nutrition and Health (10 semesters); NFS 3230 Human Nutrition (6 semesters); NFS 5230 Human Nutrition and Metabolism (28 semesters); NFS 6280 Physiology and Nutrition - for High School Science Teachers (3 semesters); NFS 6850 Controversial Issues (5 semesters); NFS7060 Research Problems (1 semester); NFS 7140 Advanced Lab techniques (1 semester), NFS 7890 Advanced Workshop on Lipid Metabolism (1 semester)